Nano-Bio-Chip Sensor Platform for Examination of Oral Exfoliative Cytology

Nano-bio-chip sensor platform for examination of oral exfoliative cytology.

Oral cancer is a deadly and disfiguring disease that could greatly benefit from new diagnostic approaches enabling early detection. In this pilot study, we describe a nano-bio-chip (NBC) sensor technique for analysis of oral cancer biomarkers in exfoliative cytology specimens, targeting both biochemical and morphologic changes associated with early oral tumorigenesis. Here, oral lesions from 41...

Improvization of conventional cytology by centrifuged liquid-based cytology in oral exfoliative cytology specimen

BACKGROUND Exfoliative cytology is the microscopic examination of shed or desquamated cells from the epithelial surface. Centrifuged liquid-based cytology (CLBC) is a modified technique that was used in the current study. AIMS To compare the efficacy of CLBC with conventional cytology in apparently normal mucosa after staining with Papanicolaou (PAP) stain. MATERIALS AND METHODS Fifty cases...

Atlas of Exfoliative Cytology

The Atlas of Exfoliative Cytology is a valuable distillate of the vast experience of the master cytologist, Dr. George N. Papanicolaou. The doubtless heavy subsidy from the Commonwealth Fund has been well employed. The book has been prepared in all modesty in loose-leaf form "to keep abreast of new advances," and an appeal is made for new material. As befits an atlas, the illustrations are many...

Quantitative Risk Stratification of Oral Leukoplakia with Exfoliative Cytology

Exfoliative cytology has been widely used for early diagnosis of oral squamous cell carcinoma (OSCC). Test outcome is reported as "negative", "atypical" (defined as abnormal epithelial changes of uncertain diagnostic significance), and "positive" (defined as definitive cellular evidence of epithelial dysplasia or carcinoma). The major challenge is how to properly manage the "atypical" patients ...

Problems of gastric exfoliative cytology.